A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10084
Swiss-prot Accession numberQ9XT35 (Sequence in FASTA format)
DescriptionParathyroid hormone precursor (Parathyrin) (PTH).
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the parathyroid hormone family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion
Protein Length115 Amino acids
Molecular weight12890
References1   Malaivijitnond S., Takenaka O.; "Nucleotide sequences of parathyroid gene in five species of macaqueof Thailand."; J. Sci. Res. Chulalongkorn Univ. 23:135-142(1998).
Domain NameParathyroid  
Hormone NameParathyroid hormone (Parathyrin) (PTH)
Mature Hormone SequenceSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFIALGAPLAPRDAGSQRPRKKEDNILVESHEKSLGEADKADVDVLTKAKSQ
Position of mature hormone in Pre-Hormone protein84 Residues from position (32-115)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10122
Swiss-prot Accession numberQ6EV78 (Sequence in FASTA format)
DescriptionLutropin subunit beta precursor (Luteinizing hormone subunit beta)(LSH-beta) (LSH-B) (LH-B) (Lutropin beta chain).
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPromotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids
Protein Length141 Amino acids
Molecular weight15183
References1  PubMed abstract 10612425
Domain NameCys_knot  
Hormone NameLuteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta)
Mature Hormone SequenceSREPLRPLCRPINATLAAEKEACPVCITVNTSICAGYCPTMMRVLQAALLPLPQVVCTYHEVRFDSIQLPGCLPGVDPVVSFPVALSCRCGPCHRSTSDCGGPKDHPLTCDHPQLPGLLFL
Position of mature hormone in Pre-Hormone protein121 Residues from position (21-141)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10279
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-18
Mature Hormone SequenceLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein18 Residues from position (86-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10329
Swiss-prot Accession numberQ6EV79 (Sequence in FASTA format)
DescriptionFollitropin subunit beta precursor (Follicle-stimulating hormone betasubunit) (FSH-beta) (FSH-B) (Follitropin beta chain).
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionStimulates development of follicle and spermatogenesis in the reproductive organs
Protein Length129 Amino acids
Molecular weight14644
References1  PubMed abstract 10612425
2  PubMed abstract 10612425
Domain NameCys_knot  
Hormone NameFollicle-stimulating hormone beta subunit
Mature Hormone SequenceNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPNIQKTCTFKEVVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFSEMKE
Position of mature hormone in Pre-Hormone protein111 Residues from position (19-129)
ReceptorP32212    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 5

HMRbase accession number10349
Swiss-prot Accession numberQ9BEH3 (Sequence in FASTA format)
DescriptionGlycoprotein hormones alpha chain precursor (Anterior pituitaryglycoprotein hormones common subunit alpha) (Follitropin alpha chain)(Follicle-stimulating hormone alpha chain) (FSH-alpha) (Lutropin alphachain) (Luteinizing hormone alpha chain) (LSH-alpha) (Thyrotropinalpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha)(Choriogonadotropin alpha chain) (Chorionic gonadotrophin alphasubunit) (CG-alpha).
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit alpha family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length120 Amino acids
Molecular weight13825
References1  PubMed abstract 11793416
2  PubMed abstract 10612425
3  PubMed abstract 11793416
4  PubMed abstract 10612425
Domain NameHormone_6  
Hormone NameGlycoprotein hormones alpha chain
Mature Hormone SequenceFPDGEFTMQDCPECKPRENKFFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSLTRVMVMGNVRVENHTQCHCSTCYYHKF
Position of mature hormone in Pre-Hormone protein96 Residues from position (25-120)
ReceptorP32212    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 6

HMRbase accession number10855
Swiss-prot Accession numberP30406 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11991
References1  PubMed abstract 6184262
Domain NameInsulin  
Hormone NameInsulin B chain
Mature Hormone SequenceFVNQHLCGSHLVEALYLVCGERGFFYTPKT
Position of mature hormone in Pre-Hormone protein30 Residues from position (25-54)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10856
Swiss-prot Accession numberP30406 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11991
References1  PubMed abstract 6184262
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number11142
Swiss-prot Accession numberP61279 (Sequence in FASTA format)
DescriptionSomatostatin precursor [Contains: Somatostatin-28; Somatostatin-14].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatostatin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSomatostatin inhibits the release of somatotropin
Protein Length116 Amino acids
Molecular weight12736
References1  PubMed abstract 2894033
Domain NameSomatostatin  
Hormone NameSomatostatin-28
Mature Hormone SequenceSANSNPAMAPRERKAGCKNFFWKTFTSC
Position of mature hormone in Pre-Hormone protein28 Residues from position (89-116)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number11143
Swiss-prot Accession numberP61279 (Sequence in FASTA format)
DescriptionSomatostatin precursor [Contains: Somatostatin-28; Somatostatin-14].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatostatin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSomatostatin inhibits the release of somatotropin
Protein Length116 Amino acids
Molecular weight12736
References1  PubMed abstract 2894033
Domain NameSomatostatin  
Hormone NameSomatostatin-14
Mature Hormone SequenceAGCKNFFWKTFTSC
Position of mature hormone in Pre-Hormone protein14 Residues from position (103-116)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number11170
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPVPPAEPAGSGLQRAEEAPRRQLRAVQRTDGESRAHLGALLARYIQQARKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS
Position of mature hormone in Pre-Hormone protein95 Residues from position (21-115)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number11171
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceAVQRTDGESRAHLGALLARYIQQARKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (46-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number11172
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-58 desnonopeptide
Mature Hormone SequenceAVQRTDGESRAHLGALLARYIQQARKAPSGRMSIIKNLQNLDPSHRISD
Position of mature hormone in Pre-Hormone protein49 Residues from position (46-94)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number11174
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-39
Mature Hormone SequenceYIQQARKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein39 Residues from position (65-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number11175
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number11176
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-25
Mature Hormone SequenceIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein25 Residues from position (79-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number11177
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (92-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number11178
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (96-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number11179
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (97-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 19

HMRbase accession number11180
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-5
Mature Hormone SequenceGWMDF
Position of mature hormone in Pre-Hormone protein5 Residues from position (99-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 20

HMRbase accession number11576
Swiss-prot Accession numberQ6DLS0 (Sequence in FASTA format)
DescriptionRenin; EC=3.4.23.15;Alternative Name: Angiotensinogenase;Precursor
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted (By similarity). Membrane (By similarity). Note=Associated to membranes via binding to ATP6AP2 (By similarity)
Developmental StageN/A
Similarity Belongs to the peptidase A1 family.
Tissue SpecificityN/A
Post translational modification N/A
Function Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney (By similarity).
Protein Length406 Amino acids
Molecular weight45011
References----
Domain NameA1_Propeptide  Asp  
Hormone NameRenin
Mature Hormone Sequence
Position of mature hormone in Pre-Hormone protein
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated